Isto Biologics (“Isto”), a biologics company dedicated to advancing bone healing, today announced the acquisition of NovaBone Products LLC (“NovaBone”), a developer and manufacturer of synthetic bone graft products, from Halma plc.
Hopkinton, MA, August 4, 2026 – Isto Biologics (“Isto”), a biologics company dedicated to advancing bone healing, today announced the acquisition of NovaBone Products LLC (“NovaBone”), a developer and manufacturer of synthetic bone graft products, from Halma plc. Supported by Keensight Capital (“Keensight”), one of the leading private equity managers dedicated to pan-European Growth Buyout[1] investments, the acquisition adds a differentiated portfolio of bioactive glass technologies and expands Isto’s ability to support surgeons with a broader range of bone graft options.
Founded in 2002 and headquartered in Alachua, Florida, NovaBone develops and manufactures synthetic bone grafts based on its proprietary bioactive glass technology, which are sold in more than 40 countries worldwide. NovaBone’s products are supported by more than 20 years of clinical evidence and used across spine, orthopedic, foot & ankle, trauma, extremities and dental procedures.
This acquisition strengthens Isto’s portfolio by adding new, differentiated synthetic products, enabling the company to provide surgeons with a broader range of bone graft substitutes. NovaBone will also reinforce Isto's presence in several surgical end-markets, while expanding its international footprint through an established presence in Europe, Asia-Pacific and LATAM. Together, the two businesses can reach a broader customer base through Isto’s commercial platform while combining complementary R&D and manufacturing strengths to drive continued innovation.
Completed just 10 months after Keensight’s investment in the business, this marks Isto’s first strategic acquisition and reflects its ambition to build a transatlantic leader in bone regeneration.
Brian Barnes, CEO, and Nate Taylor, President of Isto Biologics, said: “This acquisition is a transformative milestone for Isto. NovaBone has built a highly regarded product portfolio supported by strong clinical evidence and an excellent reputation among surgeons. The addition of its synthetic bone grafts broadens our offering and strengthens our ability to support surgeons across a wider range of procedures. We look forward to building on our shared commitment to innovation and helping patients heal faster.”
Amit Karna and David Piccoli, Partners at Keensight Capital, concluded: “Since partnering with Brian, Nate, and Isto’s management team last year, we have shared the ambition of building a leading orthobiologics platform through organic growth and targeted acquisitions. NovaBone is a highly strategic addition to Isto’s growing platform that will strengthen Isto’s product offering, expand its geographic footprint, and position the combined business as a transatlantic leader in bone regeneration.”
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About Isto Biologics
Isto Biologics, a biologics company dedicated to advancing bone healing, helps patients heal faster. With a complete portfolio of autologous therapies, synthetic bone grafts, and allograft tissue solutions, Isto’s products are used in more than 15,000 surgical procedures per month across 400+ hospitals and clinics in the U.S. www.istobiologics.com
About NovaBone
NovaBone, based in Florida since 2002, developed the first bioactive synthetic bone graft offered to the orthopedic community and has long been at the forefront of bioactive glass bone graft devices. It has developed numerous formulations and delivery systems of its patented, bioactive technology platform that results in accelerated bone growth. In total, their exclusively formulated bone graft substitute has been used for the repair of osseous defects throughout the skeletal system for over two decades and used in over two million clinical applications with unparalleled success validating the safety and efficacy of NovaBone’s technology. www.novabone.com
About Keensight Capital
Keensight Capital (“Keensight”), one of the leading European Growth Buyout firms, is committed to supporting entrepreneurs as they implement their growth strategies. With over 25 years of experience and more than €8bn of assets under management, Keensight Capital’s team of seasoned professionals leverages their differentiated private equity experience to invest in profitably growing companies generating revenues in the range of €10 million to €400 million. Drawing on its expertise in the Technology and Healthcare sectors, Keensight identifies the best investment opportunities in Europe and works closely with the management teams providing capital, strategic guidance and operational support. Keensight operates in more than 90 countries across the globe with a presence in Paris, London, Boston, and Singapore. www.keensight.com
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